A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development

نویسندگان

  • Qian Chen
  • Yang Liu
  • Steven Maere
  • Eunkyoung Lee
  • Gert Van Isterdael
  • Zidian Xie
  • Wei Xuan
  • Jessica Lucas
  • Valya Vassileva
  • Saeko Kitakura
  • Peter Marhavý
  • Krzysztof Wabnik
  • Niko Geldner
  • Eva Benková
  • Jie Le
  • Hidehiro Fukaki
  • Erich Grotewold
  • Chuanyou Li
  • Jiří Friml
  • Fred Sack
  • Tom Beeckman
  • Steffen Vanneste
چکیده

Multiple plant developmental processes, such as lateral root development, depend on auxin distribution patterns that are in part generated by the PIN-formed family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7 (ARF7) and the ARF7-regulated FOUR LIPS/MYB124 (FLP) transcription factors jointly form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription in planta to steer the early steps of lateral root formation. This regulatory mechanism might endow the PIN3 circuitry with a temporal 'memory' of auxin stimuli, potentially maintaining and enhancing the robustness of the auxin flux directionality during lateral root development. The cooperative action between canonical auxin signalling and other transcription factors might constitute a general mechanism by which transcriptional auxin-sensitivity can be regulated at a tissue-specific level.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2015